Withania Somnifera

Withania Somnifera is a plant from the Solanaceae or Nightshade family which includes the Potato, Tomato and Deadly Nightshade species. It is also known as Ashwagandha. The herbal extract has been traditionally used as a tonic and as a sedative but recent research shows that the extract contains Withanolides which have been found to have regenerative properties on brain-cell synapses in mice and in human cell lines in the laboratory.

Classification of the Plant

  • Family: Solanaceae (Potato family)
  • Genus: Withania
  • Species: Somnifera
  • Scientific Name: Withania Somnifera (Dunal)

Distribution

Withania Somnifera grows abundantly in India (especially Madhya Pradesh), Pakistan, Bangla Desh, Sri Lanka and parts of northern Africa.

Botany

  • Height: up to 170 cm
  • Shape: upright and stout shrub.
  • Leaves: alternate and ovate, up to 10 cm long and up to 5 cm wide.
  • Flowers: yellow
  • Fruit: red berries in papery protective covering (calyx).
  • Roots: long, fleshy tubers.
Withania Somnifera withania somnifera

Environmental Niche and Cultivation

  • Niche: found naturally in dry areas and in waste areas
  • Soil: sandy loam to light red soils
  • Climate required: dry climate having 65-75 cm per annum of rain and temperature of 20-38 C.
  • Altitude: up to 1500 m above sea level
  • Furrows: 60 x 60 cm; hand seeding
  • Cultivation time: 1 year - when the leaves are dry the plant is uprooted and the roots are separated from the aerial parts.
  • Fertilizers: none required
  • Diseases of the plant: leaf spot disease

Synonyms for Withania Somnifera

  • Sanskrit/Indian Name: Ashwagandha ("Ashwa" means "horse" and "gandha" means "smell": the roots of the plant have the smell of a sweaty horse.)
  • English name: Winter Cherry; Indian Ginseng.

Extracts of Withania Somnifera

  • Ashwagandha - the herbal medicine comes from the roots; the root is dried and powdered; in traditional Indian medicine toxins are removed by simmering the root in milk which is then discarded. The final product is taken orally. The extract is available in capsule form.
  • Ashwagandha Extract: the withanolide content of ashwagandha is now measured and standardized. The current formulations have the following dosages of withanolides: 1.5%; 2.5%; 4.5%; 8%. Available in capsule form. The constituents, Withanolide A, withanoside IV, and withanoside VI, have shown significant effects on the re-growth of brain-cell synapses in mice and in human cell lines in the laboratory. Further research is under way in Japan to test withanolide type molecules before testing them clinically.
  • more on Withanolide

Historical Uses of Withania Somnifera

The leaves and berries of Ashwagandha have been in use for centuries in India as a home remedy and the extract is an important part of Indian Ayurvedic medicine. It has been used in the following ways:
  • General tonic and "adaptogen", helping the body adapt to stress, especially for geriatrics; to promote strength and vigor;
  • used as sedative or calming agent and for insomnia: the species name somnifera means "sleep-bearing" in Latin;
  • Sexual vitality;
  • Liver tonic;
  • Anti-inflammatory agent; it us used to treat rheumatic pain and arthritis;
  • Coagulant: the berries are used as a substitute for rennet, to coagulate milk in cheese making.

Side Effects of Withania Somnifera

  • Ashwagandha is non-toxic at normal doses (up to 2g per day for up to 3 months);
  • At high dosages (5g per day for 30 days) some toxicity is noted (spleen, thymus, adrenal glands); longer term use (180 days) at high dosage also results in some toxicity (heart and adrenals);
  • ashwagandha has some abortifacient effects; avoid use if pregnant or lactating.

Other natural substances:

Curcuma Longa
Curcumenol (from Curcuma Phaeocaulis)
Licorice Root Extract
Petty Spurge
Rosmarinic Acid
Turmeric Extract
Vineatrol (from Grapevine shoots)
Withanolide (from Ashwagandha)
Zerumbone (from Ginger)
Withaniasomnifera.com acknowledges Pubmed (www.ncbi.nlm.nih.gov) as source for research abstracts.

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease. Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking medicines should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

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